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Vanadium in PDB 9b8y: Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius

Other elements in 9b8y:

The structure of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius also contains other interesting chemical elements:

Calcium (Ca) 8 atoms

Vanadium Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40;

Binding sites:

The binding sites of Vanadium atom in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius (pdb code 9b8y). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total 40 binding sites of Vanadium where determined in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius, PDB code: 9b8y:
Jump to Vanadium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Vanadium binding site 1 out of 40 in 9b8y

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Vanadium binding site 1 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V10 A:DVT2003 0.0 130.6 1.0
O28 A:DVT2003 1.6 130.6 1.0
O15 A:DVT2003 1.8 130.6 1.0
O27 A:DVT2003 1.9 130.6 1.0
O18 A:DVT2003 1.9 130.6 1.0
O23 A:DVT2003 2.1 130.6 1.0
O2 A:DVT2003 2.3 130.6 1.0
V8 A:DVT2003 3.0 130.6 1.0
V3 A:DVT2003 3.0 130.6 1.0
V9 A:DVT2003 3.1 130.6 1.0
V1 A:DVT2003 3.2 130.6 1.0
O17 A:DVT2003 3.5 130.6 1.0
O3 A:DVT2003 3.6 130.6 1.0
O24 A:DVT2003 3.7 130.6 1.0
O4 A:DVT2003 3.7 130.6 1.0
O10 A:DVT2003 4.3 130.6 1.0
V2 A:DVT2003 4.3 130.6 1.0
O26 A:DVT2003 4.4 130.6 1.0
O20 A:DVT2003 4.5 130.6 1.0
O5 A:DVT2003 4.5 130.6 1.0
O9 A:DVT2003 4.5 130.6 1.0
NH1 A:ARG601 4.5 103.0 1.0
O1 A:DVT2003 4.5 130.6 1.0
O8 A:DVT2003 4.6 130.6 1.0
O16 A:DVT2003 4.7 130.6 1.0
NH2 A:ARG664 5.0 85.7 1.0

Vanadium binding site 2 out of 40 in 9b8y

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Vanadium binding site 2 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 2 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V1 A:DVT2003 0.0 130.6 1.0
O5 A:DVT2003 1.6 130.6 1.0
O15 A:DVT2003 1.9 130.6 1.0
O4 A:DVT2003 1.9 130.6 1.0
O3 A:DVT2003 1.9 130.6 1.0
O1 A:DVT2003 2.0 130.6 1.0
O2 A:DVT2003 2.3 130.6 1.0
V2 A:DVT2003 3.0 130.6 1.0
V3 A:DVT2003 3.1 130.6 1.0
V9 A:DVT2003 3.1 130.6 1.0
V10 A:DVT2003 3.2 130.6 1.0
O8 A:DVT2003 3.6 130.6 1.0
O9 A:DVT2003 3.6 130.6 1.0
O27 A:DVT2003 3.6 130.6 1.0
O18 A:DVT2003 3.7 130.6 1.0
NZ A:LYS925 4.2 79.8 1.0
O26 A:DVT2003 4.4 130.6 1.0
V8 A:DVT2003 4.4 130.6 1.0
O10 A:DVT2003 4.4 130.6 1.0
O7 A:DVT2003 4.4 130.6 1.0
O28 A:DVT2003 4.5 130.6 1.0
O17 A:DVT2003 4.6 130.6 1.0
O24 A:DVT2003 4.6 130.6 1.0
O23 A:DVT2003 4.6 130.6 1.0
CE A:LYS925 4.7 79.8 1.0
O16 A:DVT2003 4.7 130.6 1.0
NH1 A:ARG664 4.7 85.7 1.0
NH2 A:ARG664 4.8 85.7 1.0

Vanadium binding site 3 out of 40 in 9b8y

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Vanadium binding site 3 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 3 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V9 A:DVT2003 0.0 130.6 1.0
O26 A:DVT2003 1.6 130.6 1.0
O4 A:DVT2003 1.8 130.6 1.0
O27 A:DVT2003 1.9 130.6 1.0
O8 A:DVT2003 2.0 130.6 1.0
O24 A:DVT2003 2.0 130.6 1.0
O2 A:DVT2003 2.2 130.6 1.0
V2 A:DVT2003 3.1 130.6 1.0
V8 A:DVT2003 3.1 130.6 1.0
V7 A:DVT2003 3.1 130.6 1.0
V1 A:DVT2003 3.1 130.6 1.0
V10 A:DVT2003 3.1 130.6 1.0
O15 A:DVT2003 3.4 130.6 1.0
O1 A:DVT2003 3.5 130.6 1.0
O23 A:DVT2003 3.5 130.6 1.0
O25 A:DVT2003 3.5 130.6 1.0
O16 A:DVT2003 3.6 130.6 1.0
NH1 A:ARG601 4.0 103.0 1.0
O21 A:DVT2003 4.3 130.6 1.0
O5 A:DVT2003 4.4 130.6 1.0
O11 A:DVT2003 4.4 130.6 1.0
O28 A:DVT2003 4.4 130.6 1.0
V3 A:DVT2003 4.4 130.6 1.0
O7 A:DVT2003 4.4 130.6 1.0
O3 A:DVT2003 4.4 130.6 1.0
O20 A:DVT2003 4.4 130.6 1.0
O18 A:DVT2003 4.5 130.6 1.0
O9 A:DVT2003 4.5 130.6 1.0
O17 A:DVT2003 4.5 130.6 1.0

Vanadium binding site 4 out of 40 in 9b8y

Go back to Vanadium Binding Sites List in 9b8y
Vanadium binding site 4 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 4 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V7 A:DVT2003 0.0 130.6 1.0
O25 A:DVT2003 1.6 130.6 1.0
O11 A:DVT2003 1.8 130.6 1.0
O21 A:DVT2003 1.8 130.6 1.0
O24 A:DVT2003 2.0 130.6 1.0
O8 A:DVT2003 2.0 130.6 1.0
O16 A:DVT2003 2.2 130.6 1.0
V5 A:DVT2003 3.0 130.6 1.0
V9 A:DVT2003 3.1 130.6 1.0
V6 A:DVT2003 3.1 130.6 1.0
V2 A:DVT2003 3.1 130.6 1.0
V8 A:DVT2003 3.2 130.6 1.0
O6 A:DVT2003 3.3 130.6 1.0
O7 A:DVT2003 3.4 130.6 1.0
O26 A:DVT2003 3.5 130.6 1.0
O20 A:DVT2003 3.5 130.6 1.0
O2 A:DVT2003 3.7 130.6 1.0
O4 A:DVT2003 4.3 130.6 1.0
O14 A:DVT2003 4.3 130.6 1.0
O22 A:DVT2003 4.4 130.6 1.0
O13 A:DVT2003 4.4 130.6 1.0
O27 A:DVT2003 4.4 130.6 1.0
V4 A:DVT2003 4.4 130.6 1.0
O19 A:DVT2003 4.4 130.6 1.0
O1 A:DVT2003 4.5 130.6 1.0
O23 A:DVT2003 4.5 130.6 1.0
O9 A:DVT2003 4.6 130.6 1.0
O17 A:DVT2003 4.6 130.6 1.0

Vanadium binding site 5 out of 40 in 9b8y

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Vanadium binding site 5 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 5 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V6 A:DVT2003 0.0 130.6 1.0
O22 A:DVT2003 1.6 130.6 1.0
O6 A:DVT2003 1.9 130.6 1.0
O21 A:DVT2003 1.9 130.6 1.0
O19 A:DVT2003 1.9 130.6 1.0
O20 A:DVT2003 2.0 130.6 1.0
O16 A:DVT2003 2.3 130.6 1.0
V8 A:DVT2003 3.0 130.6 1.0
V7 A:DVT2003 3.1 130.6 1.0
V4 A:DVT2003 3.1 130.6 1.0
V5 A:DVT2003 3.1 130.6 1.0
O24 A:DVT2003 3.5 130.6 1.0
O17 A:DVT2003 3.6 130.6 1.0
O11 A:DVT2003 3.6 130.6 1.0
O13 A:DVT2003 3.7 130.6 1.0
NZ A:LYS613 3.9 102.5 1.0
V2 A:DVT2003 4.4 130.6 1.0
O25 A:DVT2003 4.4 130.6 1.0
O12 A:DVT2003 4.4 130.6 1.0
O23 A:DVT2003 4.4 130.6 1.0
O14 A:DVT2003 4.5 130.6 1.0
O8 A:DVT2003 4.6 130.6 1.0
O7 A:DVT2003 4.6 130.6 1.0
O9 A:DVT2003 4.6 130.6 1.0
O2 A:DVT2003 4.7 130.6 1.0

Vanadium binding site 6 out of 40 in 9b8y

Go back to Vanadium Binding Sites List in 9b8y
Vanadium binding site 6 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 6 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V8 A:DVT2003 0.0 130.6 1.0
O23 A:DVT2003 1.7 130.6 1.0
O20 A:DVT2003 1.7 130.6 1.0
O17 A:DVT2003 1.9 130.6 1.0
O24 A:DVT2003 1.9 130.6 1.0
O2 A:DVT2003 2.1 130.6 1.0
O16 A:DVT2003 2.1 130.6 1.0
V10 A:DVT2003 3.0 130.6 1.0
O27 A:DVT2003 3.0 130.6 1.0
V6 A:DVT2003 3.0 130.6 1.0
V9 A:DVT2003 3.1 130.6 1.0
O19 A:DVT2003 3.1 130.6 1.0
V4 A:DVT2003 3.1 130.6 1.0
V2 A:DVT2003 3.1 130.6 1.0
O18 A:DVT2003 3.1 130.6 1.0
O21 A:DVT2003 3.1 130.6 1.0
V3 A:DVT2003 3.1 130.6 1.0
V7 A:DVT2003 3.2 130.6 1.0
O9 A:DVT2003 3.4 130.6 1.0
O8 A:DVT2003 3.4 130.6 1.0
NZ A:LYS613 3.8 102.5 1.0
O28 A:DVT2003 4.3 130.6 1.0
O22 A:DVT2003 4.3 130.6 1.0
O15 A:DVT2003 4.3 130.6 1.0
O6 A:DVT2003 4.3 130.6 1.0
V5 A:DVT2003 4.3 130.6 1.0
O13 A:DVT2003 4.3 130.6 1.0
O4 A:DVT2003 4.3 130.6 1.0
O26 A:DVT2003 4.4 130.6 1.0
O3 A:DVT2003 4.4 130.6 1.0
O7 A:DVT2003 4.4 130.6 1.0
V1 A:DVT2003 4.4 130.6 1.0
O12 A:DVT2003 4.4 130.6 1.0
O1 A:DVT2003 4.4 130.6 1.0
O11 A:DVT2003 4.4 130.6 1.0
O10 A:DVT2003 4.4 130.6 1.0
O25 A:DVT2003 4.5 130.6 1.0
NH1 A:ARG601 4.8 103.0 1.0
CE A:LYS613 4.8 102.5 1.0

Vanadium binding site 7 out of 40 in 9b8y

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Vanadium binding site 7 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 7 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V5 A:DVT2003 0.0 130.6 1.0
O14 A:DVT2003 1.6 130.6 1.0
O6 A:DVT2003 1.8 130.6 1.0
O11 A:DVT2003 1.9 130.6 1.0
O13 A:DVT2003 1.9 130.6 1.0
O7 A:DVT2003 2.1 130.6 1.0
O16 A:DVT2003 2.3 130.6 1.0
V7 A:DVT2003 3.0 130.6 1.0
V2 A:DVT2003 3.0 130.6 1.0
V4 A:DVT2003 3.1 130.6 1.0
V6 A:DVT2003 3.1 130.6 1.0
O8 A:DVT2003 3.6 130.6 1.0
O21 A:DVT2003 3.6 130.6 1.0
O19 A:DVT2003 3.6 130.6 1.0
O9 A:DVT2003 3.6 130.6 1.0
O25 A:DVT2003 4.3 130.6 1.0
V8 A:DVT2003 4.3 130.6 1.0
O12 A:DVT2003 4.4 130.6 1.0
O22 A:DVT2003 4.4 130.6 1.0
O24 A:DVT2003 4.5 130.6 1.0
O1 A:DVT2003 4.5 130.6 1.0
O20 A:DVT2003 4.5 130.6 1.0
O17 A:DVT2003 4.5 130.6 1.0
O2 A:DVT2003 4.7 130.6 1.0

Vanadium binding site 8 out of 40 in 9b8y

Go back to Vanadium Binding Sites List in 9b8y
Vanadium binding site 8 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 8 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V2 A:DVT2003 0.0 130.6 1.0
O7 A:DVT2003 1.7 130.6 1.0
O1 A:DVT2003 1.7 130.6 1.0
O8 A:DVT2003 1.9 130.6 1.0
O9 A:DVT2003 1.9 130.6 1.0
O16 A:DVT2003 2.1 130.6 1.0
O2 A:DVT2003 2.1 130.6 1.0
V5 A:DVT2003 3.0 130.6 1.0
O4 A:DVT2003 3.0 130.6 1.0
O13 A:DVT2003 3.0 130.6 1.0
V1 A:DVT2003 3.0 130.6 1.0
V9 A:DVT2003 3.1 130.6 1.0
O3 A:DVT2003 3.1 130.6 1.0
V4 A:DVT2003 3.1 130.6 1.0
V8 A:DVT2003 3.1 130.6 1.0
V7 A:DVT2003 3.1 130.6 1.0
V3 A:DVT2003 3.1 130.6 1.0
O11 A:DVT2003 3.2 130.6 1.0
O24 A:DVT2003 3.4 130.6 1.0
O17 A:DVT2003 3.4 130.6 1.0
O14 A:DVT2003 4.3 130.6 1.0
O5 A:DVT2003 4.3 130.6 1.0
O15 A:DVT2003 4.3 130.6 1.0
O27 A:DVT2003 4.3 130.6 1.0
O6 A:DVT2003 4.3 130.6 1.0
V10 A:DVT2003 4.3 130.6 1.0
O21 A:DVT2003 4.4 130.6 1.0
O26 A:DVT2003 4.4 130.6 1.0
O19 A:DVT2003 4.4 130.6 1.0
O25 A:DVT2003 4.4 130.6 1.0
V6 A:DVT2003 4.4 130.6 1.0
O23 A:DVT2003 4.4 130.6 1.0
O18 A:DVT2003 4.4 130.6 1.0
O20 A:DVT2003 4.4 130.6 1.0
O12 A:DVT2003 4.4 130.6 1.0
O10 A:DVT2003 4.4 130.6 1.0
CE A:LYS925 4.9 79.8 1.0

Vanadium binding site 9 out of 40 in 9b8y

Go back to Vanadium Binding Sites List in 9b8y
Vanadium binding site 9 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 9 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V4 A:DVT2003 0.0 130.6 1.0
O12 A:DVT2003 1.6 130.6 1.0
O13 A:DVT2003 1.8 130.6 1.0
O19 A:DVT2003 1.8 130.6 1.0
O17 A:DVT2003 2.0 130.6 1.0
O9 A:DVT2003 2.0 130.6 1.0
O16 A:DVT2003 2.2 130.6 1.0
V5 A:DVT2003 3.1 130.6 1.0
V8 A:DVT2003 3.1 130.6 1.0
V2 A:DVT2003 3.1 130.6 1.0
V6 A:DVT2003 3.1 130.6 1.0
V3 A:DVT2003 3.1 130.6 1.0
O6 A:DVT2003 3.3 130.6 1.0
O20 A:DVT2003 3.4 130.6 1.0
O7 A:DVT2003 3.5 130.6 1.0
O10 A:DVT2003 3.5 130.6 1.0
O2 A:DVT2003 3.6 130.6 1.0
O18 A:DVT2003 4.3 130.6 1.0
O14 A:DVT2003 4.3 130.6 1.0
O3 A:DVT2003 4.4 130.6 1.0
O22 A:DVT2003 4.4 130.6 1.0
V7 A:DVT2003 4.4 130.6 1.0
O21 A:DVT2003 4.4 130.6 1.0
O23 A:DVT2003 4.4 130.6 1.0
O11 A:DVT2003 4.5 130.6 1.0
O1 A:DVT2003 4.5 130.6 1.0
O24 A:DVT2003 4.5 130.6 1.0
O8 A:DVT2003 4.6 130.6 1.0

Vanadium binding site 10 out of 40 in 9b8y

Go back to Vanadium Binding Sites List in 9b8y
Vanadium binding site 10 out of 40 in the Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 10 of Cryo-Em Structure of the Human TRPM4 Channel in Complex with Calcium and Decavanadate at 37 Degrees Celsius within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2003

b:130.6
occ:1.00
V3 A:DVT2003 0.0 130.6 1.0
O10 A:DVT2003 1.6 130.6 1.0
O3 A:DVT2003 1.8 130.6 1.0
O18 A:DVT2003 1.8 130.6 1.0
O9 A:DVT2003 2.0 130.6 1.0
O17 A:DVT2003 2.0 130.6 1.0
O2 A:DVT2003 2.2 130.6 1.0
V10 A:DVT2003 3.0 130.6 1.0
V1 A:DVT2003 3.1 130.6 1.0
V4 A:DVT2003 3.1 130.6 1.0
V2 A:DVT2003 3.1 130.6 1.0
V8 A:DVT2003 3.1 130.6 1.0
O15 A:DVT2003 3.3 130.6 1.0
O1 A:DVT2003 3.4 130.6 1.0
O23 A:DVT2003 3.5 130.6 1.0
O12 A:DVT2003 3.5 130.6 1.0
O16 A:DVT2003 3.7 130.6 1.0
O13 A:DVT2003 4.3 130.6 1.0
O28 A:DVT2003 4.3 130.6 1.0
O27 A:DVT2003 4.4 130.6 1.0
O4 A:DVT2003 4.4 130.6 1.0
O19 A:DVT2003 4.4 130.6 1.0
O5 A:DVT2003 4.4 130.6 1.0
V9 A:DVT2003 4.4 130.6 1.0
O7 A:DVT2003 4.5 130.6 1.0
O20 A:DVT2003 4.5 130.6 1.0
O8 A:DVT2003 4.6 130.6 1.0
O24 A:DVT2003 4.6 130.6 1.0
NH2 A:ARG664 4.6 85.7 1.0

Reference:

J.Hu, S.J.Park, T.Walter, I.J.Orozco, G.O'dea, X.Ye, J.Du, W.Lu. Physiological Temperature Drives TRPM4 Ligand Recognition and Gating Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07436-7
Page generated: Fri Oct 11 20:46:26 2024

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