Vanadium in PDB 8oxc: Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi

All present enzymatic activity of Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi:
7.6.2.1;

The structure of Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Vanadium atom in the Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi (pdb code 8oxc). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi, PDB code: 8oxc:

Vanadium binding site 1 out of 1 in the Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Cryo-Em Structure of ATP8B1-CDC50A in E2-Pi Conformation with Occluded Pi within 5.0Å range: probe atom residue distance (Å) B Occ A:V1201 b:48.9 occ:1.00 V A:VN41201 0.0 48.9 1.0 O3 A:VN41201 1.7 48.9 1.0 O1 A:VN41201 1.7 48.9 1.0 O2 A:VN41201 1.7 48.9 1.0 O A:HOH1306 1.9 53.1 1.0 OD1 A:ASP454 2.1 48.7 1.0 CG A:ASP454 3.2 48.7 1.0 OG1 A:THR732 3.4 50.6 1.0 CG2 A:THR456 3.5 50.7 1.0 ND2 A:ASN896 3.6 49.1 1.0 N A:GLY733 3.6 52.5 1.0 OD2 A:ASP454 3.7 48.7 1.0 MG A:MG1202 3.8 41.9 1.0 NZ A:LYS873 3.9 47.8 1.0 CA A:THR732 3.9 50.6 1.0 OE2 A:GLU234 4.0 57.0 1.0 N A:GLY233 4.0 54.1 1.0 CA A:GLY233 4.0 54.1 1.0 N A:THR456 4.2 50.7 1.0 CB A:THR732 4.2 50.6 1.0 N A:LYS455 4.2 51.1 1.0 C A:THR732 4.3 50.6 1.0 CB A:ASP454 4.4 48.7 1.0 O A:THR456 4.5 50.7 1.0 CA A:GLY733 4.6 52.5 1.0 CB A:THR456 4.6 50.7 1.0 O A:LEU731 4.7 48.6 1.0 C A:GLY233 4.8 54.1 1.0 CE A:LYS873 4.8 47.8 1.0 CA A:ASP454 4.8 48.7 1.0 CG A:ASN896 4.8 49.1 1.0 N A:ASP734 4.9 56.4 1.0 CA A:THR456 4.9 50.7 1.0 OD1 A:ASP897 4.9 47.5 1.0

T.Dieudonne, F.Kummerer, M.J.Laursen, C.Stock, R.K.Flygaard, S.Khalid, G.Lenoir, J.A.Lyons, K.Lindorff-Larsen, P.Nissen. Activation and Substrate Specificity of the Human P4-Atpase ATP8B1. Nat Commun V. 14 7492 2023.
ISSN: ESSN 2041-1723
PubMed: 37980352
DOI: 10.1038/S41467-023-42828-9