Vanadium in PDB 8k7b: Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)

All present enzymatic activity of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound):
7.6.2.5;

The structure of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Vanadium atom in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) (pdb code 8k7b). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total 2 binding sites of Vanadium where determined in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound), PDB code: 8k7b:
Jump to Vanadium binding site number: 1; 2;

Vanadium binding site 1 out of 2 in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) within 5.0Å range: probe atom residue distance (Å) B Occ A:V902 b:30.0 occ:1.00 VG A:AOV902 0.0 30.0 1.0 O4G A:AOV902 2.1 30.0 1.0 O3G A:AOV902 2.1 30.0 1.0 O2G A:AOV902 2.1 30.0 1.0 O3B A:AOV902 2.1 30.0 1.0 O1G A:AOV902 2.1 30.0 1.0 O1B A:AOV902 2.9 30.0 1.0 PB A:AOV902 3.0 30.0 1.0 MG A:MG903 3.4 20.0 1.0 O2B A:AOV902 3.8 30.0 1.0 N A:GLY626 4.3 85.5 1.0 O3A A:AOV902 4.4 30.0 1.0 NE2 A:HIS783 4.6 89.8 1.0 OE1 A:GLN671 4.6 67.8 1.0 CE A:LYS629 4.7 74.6 1.0 CA A:SER625 4.8 90.0 1.0 CA B:GLY729 4.9 74.0 1.0

Vanadium binding site 2 out of 2 in the Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound)


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 2 of Post-Occluded Structure of Human ABCB6 W546A Mutant (Adp/VO4-Bound) within 5.0Å range: probe atom residue distance (Å) B Occ B:V902 b:30.0 occ:1.00 VG B:AOV902 0.0 30.0 1.0 O4G B:AOV902 2.1 30.0 1.0 O3G B:AOV902 2.1 30.0 1.0 O1G B:AOV902 2.1 30.0 1.0 O2G B:AOV902 2.1 30.0 1.0 O3B B:AOV902 2.1 30.0 1.0 O2B B:AOV902 3.0 30.0 1.0 PB B:AOV902 3.0 30.0 1.0 O1B B:AOV902 3.7 30.0 1.0 MG B:MG903 3.8 20.0 1.0 NE2 B:HIS783 4.2 89.3 1.0 CE B:LYS629 4.5 71.3 1.0 O3A B:AOV902 4.5 30.0 1.0 NZ B:LYS629 4.7 71.3 1.0 N B:GLY626 4.7 82.1 1.0 OG B:SER625 4.7 84.6 1.0 CA A:GLY729 4.8 71.6 1.0 CA B:SER625 4.9 84.6 1.0 CE1 B:HIS783 4.9 89.3 1.0

S.S.Lee, J.G.Park, E.Jang, S.H.Choi, S.Kim, J.W.Kim, M.S.Jin. W546 Stacking Disruption Traps the Human Porphyrin Transporter ABCB6 in An Outward-Facing Transient State. Commun Biol V. 6 960 2023.
ISSN: ESSN 2399-3642
PubMed: 37735522
DOI: 10.1038/S42003-023-05339-3