Vanadium in PDB 7l0m: Vanadate-Bound Yoph G352T

All present enzymatic activity of Vanadate-Bound Yoph G352T:
3.1.3.48;

The structure of Vanadate-Bound Yoph G352T, PDB code: 7l0m was solved by R.D.Shen, A.C.Hengge, S.J.Johnson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.15 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.231, 56.091, 98.302, 90, 90, 90
R / Rfree (%)	17.8 / 22.6

The binding sites of Vanadium atom in the Vanadate-Bound Yoph G352T (pdb code 7l0m). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Vanadate-Bound Yoph G352T, PDB code: 7l0m:

Vanadium binding site 1 out of 1 in the Vanadate-Bound Yoph G352T


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Vanadate-Bound Yoph G352T within 5.0Å range: probe atom residue distance (Å) B Occ A:V501 b:31.8 occ:1.00 V A:VO4501 0.0 31.8 1.0 O2 A:VO4501 1.8 24.5 1.0 O4 A:VO4501 1.8 29.4 1.0 O1 A:VO4501 1.8 26.9 1.0 O3 A:VO4501 1.8 28.2 1.0 SG A:CYS403 2.8 27.4 1.0 OD2 A:ASP356 3.7 34.5 1.0 N A:GLY408 3.7 25.5 1.0 CB A:CYS403 3.8 21.5 1.0 NE A:ARG409 3.9 28.2 1.0 N A:ALA405 3.9 20.9 1.0 N A:ARG409 3.9 23.1 1.0 CA A:GLY408 3.9 23.7 1.0 NH2 A:ARG409 3.9 26.0 1.0 O A:HOH613 4.1 36.0 1.0 NE2 A:GLN446 4.1 32.0 1.0 N A:ARG404 4.2 24.1 1.0 N A:GLY406 4.2 23.9 1.0 CB A:ALA405 4.3 26.8 1.0 CZ A:ARG409 4.4 29.5 1.0 N A:VAL407 4.4 21.7 1.0 C A:GLY408 4.5 25.4 1.0 CA A:ALA405 4.5 22.0 1.0 CG A:ASP356 4.6 37.2 1.0 C A:ALA405 4.8 25.2 1.0 C A:VAL407 4.8 25.0 1.0 CB A:ARG404 4.9 22.9 1.0 C A:ARG404 4.9 24.9 1.0 OD1 A:ASP356 4.9 38.8 1.0 CA A:ARG404 4.9 23.1 1.0 CG A:ARG409 4.9 25.9 1.0 CB A:ARG409 4.9 22.0 1.0 CG2 A:VAL407 4.9 22.2 1.0 CD A:ARG409 5.0 28.0 1.0 O A:HOH698 5.0 34.5 1.0

R.Shen, R.M.Crean, S.J.Johnson, S.C.L.Kamerlin, A.C.Hengge. Single Residue on the Wpd-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases Jacs Au 2021.
DOI: 10.1021/JACSAU.1C00054