Atomistry » Vanadium » PDB 6raj-7q0u » 6xef
Atomistry »
  Vanadium »
    PDB 6raj-7q0u »
      6xef »

Vanadium in PDB 6xef: Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate

Enzymatic activity of Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate

All present enzymatic activity of Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate:
3.1.3.48;

Protein crystallography data

The structure of Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate, PDB code: 6xef was solved by K.J.Olsen, R.Shen, S.J.Johnson, A.C.Hengge, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.19 / 2.05
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 88.384, 88.384, 104.879, 90, 90, 120
R / Rfree (%) 18.1 / 20.3

Other elements in 6xef:

The structure of Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Vanadium Binding Sites:

The binding sites of Vanadium atom in the Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate (pdb code 6xef). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate, PDB code: 6xef:

Vanadium binding site 1 out of 1 in 6xef

Go back to Vanadium Binding Sites List in 6xef
Vanadium binding site 1 out of 1 in the Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Crystal Structure of the PTP1B Yoph Wpd Loop Chimera 4 Bound to Vanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V404

b:42.5
occ:0.91
 V A:VO4404 0.0 42.5 0.9
O2 A:VO4404 1.8 37.3 0.9
O4 A:VO4404 1.8 38.1 0.9
O3 A:VO4404 1.8 36.8 0.9
O1 A:VO4404 1.8 52.5 0.9
SG A:CYS215 2.6 37.8 1.0
CB A:CYS215 3.5 35.1 1.0
N A:GLY220 3.7 40.5 1.0
OD1 A:ASP181 3.7 56.1 1.0
N A:ALA217 3.8 32.3 1.0
OE1 A:GLN262 3.8 47.5 0.5
O A:HOH541 3.9 44.3 1.0
NE A:ARG221 4.0 40.6 1.0
NH2 A:ARG221 4.0 38.7 1.0
N A:ARG221 4.0 39.3 1.0
N A:SER216 4.0 33.5 1.0
CA A:GLY220 4.1 35.6 1.0
N A:GLY218 4.2 36.9 1.0
CB A:ALA217 4.2 36.6 1.0
N A:ILE219 4.4 38.2 1.0
CZ A:ARG221 4.4 43.4 1.0
CA A:ALA217 4.5 34.9 1.0
C A:GLY220 4.6 41.2 1.0
CG A:ASP181 4.6 57.5 1.0
CA A:CYS215 4.7 32.5 1.0
C A:ALA217 4.8 36.0 1.0
CA A:SER216 4.8 33.0 1.0
C A:SER216 4.8 33.8 1.0
C A:CYS215 4.8 33.4 1.0
CB A:ARG221 4.8 36.9 1.0
OD2 A:ASP181 4.8 63.0 1.0
CD A:GLN262 4.8 46.3 0.5
C A:ILE219 4.9 37.8 1.0
CB A:SER216 4.9 38.6 1.0
CG A:ARG221 4.9 40.6 1.0
CA A:ARG221 5.0 37.6 1.0

Reference:

R.Shen, K.J.Olsen, S.J.Johnson, A.C.Hengge. Insights From PTP1B Yoph Chimeras Into the Importance of Wpd-Loop Sequence For Activity and Structure in Protein Tyrosine Phosphatases To Be Published.
Page generated: Fri Oct 11 20:32:07 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy