Vanadium in PDB 6rvz: Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate

The structure of Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate, PDB code: 6rvz was solved by A.Kroupova, M.Jinek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.04 / 2.10
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	99.653, 99.653, 94.155, 90.00, 90.00, 120.00
R / Rfree (%)	18.8 / 21.1

The structure of Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Potassium	(K)	3 atoms

The binding sites of Vanadium atom in the Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate (pdb code 6rvz). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate, PDB code: 6rvz:

Vanadium binding site 1 out of 1 in the Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Crystal Structure of ANGEL2, A 2',3'-Cyclic Phosphatase, in Complex with Adenosine-2',3'-Vanadate within 5.0Å range: probe atom residue distance (Å) B Occ A:V601 b:30.8 occ:1.00 V A:KL2601 0.0 30.8 1.0 O2V A:KL2601 2.0 31.4 1.0 O2' A:KL2601 2.0 30.6 1.0 O3' A:KL2601 2.0 30.7 1.0 O3V A:KL2601 2.1 30.4 1.0 O1V A:KL2601 2.1 30.4 1.0 HOV3 A:KL2601 2.7 30.0 0.0 HOV1 A:KL2601 2.7 30.0 0.0 C2' A:KL2601 2.8 31.4 1.0 C3' A:KL2601 2.9 31.1 1.0 MG A:MG602 3.0 25.6 1.0 H2' A:KL2601 3.1 31.2 1.0 HE2 A:HIS310 3.2 26.2 0.0 HE2 A:HIS533 3.3 25.1 0.0 H4' A:KL2601 3.6 31.2 1.0 HD21 A:ASN353 3.7 25.3 0.0 H3' A:KL2601 3.7 31.1 1.0 O A:HOH716 3.7 19.4 1.0 OD1 A:ASN353 3.8 25.9 1.0 O A:HOH791 3.8 33.5 1.0 OD2 A:ASP351 3.8 26.2 1.0 O A:HOH787 3.8 26.6 1.0 C4' A:KL2601 3.8 31.3 1.0 HD1 A:TYR313 3.8 28.1 1.0 HD21 A:ASN173 3.9 23.5 0.0 OE2 A:GLU220 3.9 25.5 1.0 NE2 A:HIS310 4.0 25.5 1.0 HE1 A:HIS310 4.1 25.6 1.0 NE2 A:HIS533 4.1 26.1 1.0 C1' A:KL2601 4.2 31.6 1.0 HE1 A:HIS533 4.3 26.3 1.0 ND2 A:ASN353 4.4 25.1 1.0 CD1 A:TYR313 4.4 28.0 1.0 H1' A:KL2601 4.4 31.6 1.0 CE1 A:HIS310 4.4 25.8 1.0 ND2 A:ASN173 4.4 23.4 1.0 HD22 A:ASN173 4.5 23.5 0.0 CG A:ASN353 4.5 25.5 1.0 CE1 A:HIS533 4.6 26.5 1.0 O A:HOH754 4.6 20.1 1.0 HE1 A:TYR313 4.6 28.8 1.0 O4' A:KL2601 4.6 31.3 1.0 CG A:ASP351 4.7 26.1 1.0 O A:HOH814 4.7 24.6 1.0 HB2 A:TYR313 4.7 26.6 1.0 HG22 A:VAL478 4.7 25.9 1.0 O A:HOH889 4.7 39.1 1.0 H5'1 A:KL2601 4.8 31.0 1.0 CE1 A:TYR313 4.8 28.9 1.0 OD1 A:ASP351 4.9 26.0 1.0 O A:HOH926 4.9 48.1 1.0 C5' A:KL2601 5.0 31.2 1.0

P.Pinto, A.Kroupova, M.Jinek, S.Weitzer, J.Martinez. ANGEL2, A Member of the CCR4-Not Family of Deadenylases, Is A Mammalian 2,3-Cyclic Phosphatase. To Be Published.