Vanadium in PDB 6i7e: Plasmodium Falciparum Myosin A, Pre-Powerstroke

The structure of Plasmodium Falciparum Myosin A, Pre-Powerstroke, PDB code: 6i7e was solved by J.Robert-Paganin, D.Auguin, D.Moussaoui, G.Jousset, J.Baum, K.M.Trybus, A.Houdusse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.17 / 3.49
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	197.460, 197.460, 178.144, 90.00, 90.00, 120.00
R / Rfree (%)	19.3 / 23.3

The structure of Plasmodium Falciparum Myosin A, Pre-Powerstroke also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Vanadium atom in the Plasmodium Falciparum Myosin A, Pre-Powerstroke (pdb code 6i7e). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Plasmodium Falciparum Myosin A, Pre-Powerstroke, PDB code: 6i7e:

Vanadium binding site 1 out of 1 in the Plasmodium Falciparum Myosin A, Pre-Powerstroke


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Plasmodium Falciparum Myosin A, Pre-Powerstroke within 5.0Å range: probe atom residue distance (Å) B Occ A:V803 b:0.1 occ:1.00 V A:VO4803 0.0 0.1 1.0 O4 A:VO4803 1.5 1.0 1.0 O3 A:VO4803 1.6 0.1 1.0 O1 A:VO4803 1.6 0.8 1.0 O2 A:VO4803 1.6 0.7 1.0 O2B A:ADP801 2.8 0.2 1.0 OG A:SER193 3.2 0.2 1.0 O1B A:ADP801 3.4 0.4 1.0 PB A:ADP801 3.5 0.2 1.0 OG A:SER245 3.5 0.6 1.0 N A:SER246 3.6 0.3 1.0 MG A:MG802 3.7 0.5 1.0 CA A:SER193 4.0 0.7 1.0 O3B A:ADP801 4.1 0.9 1.0 CA A:SER245 4.1 0.3 1.0 CB A:SER193 4.1 0.6 1.0 N A:GLY194 4.2 0.7 1.0 CB A:SER246 4.2 0.6 1.0 C A:SER193 4.3 0.5 1.0 NZ A:LYS197 4.3 0.6 1.0 C A:SER245 4.3 0.0 1.0 CB A:SER245 4.4 1.0 1.0 O A:SER246 4.4 0.2 1.0 CA A:SER246 4.4 0.7 1.0 N A:GLY472 4.4 0.5 1.0 CA A:PHE471 4.4 0.1 1.0 ND2 A:ASN242 4.4 0.5 1.0 O A:ILE470 4.6 0.6 1.0 OG1 A:THR198 4.8 0.6 1.0 C A:SER246 4.8 0.1 1.0 NH2 A:ARG247 4.9 0.3 1.0 CB A:PHE471 4.9 0.4 1.0 O A:ASN244 4.9 0.0 1.0 O2A A:ADP801 4.9 0.6 1.0 O3A A:ADP801 4.9 0.9 1.0 C A:PHE471 5.0 0.9 1.0 OG A:SER246 5.0 0.0 1.0

J.Robert-Paganin, J.P.Robblee, D.Auguin, T.C.A.Blake, C.S.Bookwalter, E.B.Krementsova, D.Moussaoui, M.J.Previs, G.Jousset, J.Baum, K.M.Trybus, A.Houdusse. Plasmodium Myosin A Drives Parasite Invasion By An Atypical Force Generating Mechanism. Nat Commun V. 10 3286 2019.
ISSN: ESSN 2041-1723
PubMed: 31337750
DOI: 10.1038/S41467-019-11120-0