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Vanadium in PDB 5wp6: Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate

Vanadium Binding Sites:

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>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 80;

Binding sites:

The binding sites of Vanadium atom in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate (pdb code 5wp6). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total 80 binding sites of Vanadium where determined in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate, PDB code: 5wp6:
Jump to Vanadium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Vanadium binding site 1 out of 80 in 5wp6

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Vanadium binding site 1 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V10 A:DVT2001 0.0 20.0 1.0
O28 A:DVT2001 1.6 20.0 1.0
O15 A:DVT2001 1.9 20.0 1.0
O27 A:DVT2001 1.9 20.0 1.0
O18 A:DVT2001 1.9 20.0 1.0
O23 A:DVT2001 2.1 20.0 1.0
O2 A:DVT2001 2.3 20.0 1.0
V8 A:DVT2001 3.0 20.0 1.0
V3 A:DVT2001 3.0 20.0 1.0
V9 A:DVT2001 3.1 20.0 1.0
V1 A:DVT2001 3.2 20.0 1.0
O17 A:DVT2001 3.6 20.0 1.0
O3 A:DVT2001 3.6 20.0 1.0
O24 A:DVT2001 3.7 20.0 1.0
O4 A:DVT2001 3.7 20.0 1.0
O10 A:DVT2001 4.3 20.0 1.0
V2 A:DVT2001 4.4 20.0 1.0
O26 A:DVT2001 4.4 20.0 1.0
O5 A:DVT2001 4.5 20.0 1.0
O20 A:DVT2001 4.5 20.0 1.0
O9 A:DVT2001 4.5 20.0 1.0
O1 A:DVT2001 4.6 20.0 1.0
O8 A:DVT2001 4.6 20.0 1.0
O7 A:DVT2001 4.7 20.0 1.0

Vanadium binding site 2 out of 80 in 5wp6

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Vanadium binding site 2 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 2 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V1 A:DVT2001 0.0 20.0 1.0
O5 A:DVT2001 1.6 20.0 1.0
O15 A:DVT2001 1.9 20.0 1.0
O4 A:DVT2001 1.9 20.0 1.0
O3 A:DVT2001 1.9 20.0 1.0
O1 A:DVT2001 2.0 20.0 1.0
O2 A:DVT2001 2.3 20.0 1.0
V2 A:DVT2001 3.0 20.0 1.0
V3 A:DVT2001 3.1 20.0 1.0
V9 A:DVT2001 3.1 20.0 1.0
V10 A:DVT2001 3.2 20.0 1.0
O8 A:DVT2001 3.6 20.0 1.0
O9 A:DVT2001 3.6 20.0 1.0
O27 A:DVT2001 3.6 20.0 1.0
O18 A:DVT2001 3.7 20.0 1.0
O26 A:DVT2001 4.4 20.0 1.0
V8 A:DVT2001 4.4 20.0 1.0
O10 A:DVT2001 4.4 20.0 1.0
O16 A:DVT2001 4.5 20.0 1.0
O28 A:DVT2001 4.5 20.0 1.0
O17 A:DVT2001 4.6 20.0 1.0
O24 A:DVT2001 4.6 20.0 1.0
O23 A:DVT2001 4.6 20.0 1.0
O7 A:DVT2001 4.7 20.0 1.0

Vanadium binding site 3 out of 80 in 5wp6

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Vanadium binding site 3 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 3 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V9 A:DVT2001 0.0 20.0 1.0
O26 A:DVT2001 1.6 20.0 1.0
O4 A:DVT2001 1.8 20.0 1.0
O27 A:DVT2001 1.9 20.0 1.0
O8 A:DVT2001 2.0 20.0 1.0
O24 A:DVT2001 2.0 20.0 1.0
O2 A:DVT2001 2.2 20.0 1.0
V2 A:DVT2001 3.1 20.0 1.0
V8 A:DVT2001 3.1 20.0 1.0
V7 A:DVT2001 3.1 20.0 1.0
V1 A:DVT2001 3.1 20.0 1.0
V10 A:DVT2001 3.1 20.0 1.0
O15 A:DVT2001 3.4 20.0 1.0
O1 A:DVT2001 3.5 20.0 1.0
O23 A:DVT2001 3.5 20.0 1.0
O25 A:DVT2001 3.5 20.0 1.0
O7 A:DVT2001 3.6 20.0 1.0
O21 A:DVT2001 4.3 20.0 1.0
O5 A:DVT2001 4.4 20.0 1.0
O11 A:DVT2001 4.4 20.0 1.0
O28 A:DVT2001 4.4 20.0 1.0
V3 A:DVT2001 4.4 20.0 1.0
O16 A:DVT2001 4.4 20.0 1.0
O3 A:DVT2001 4.4 20.0 1.0
O20 A:DVT2001 4.5 20.0 1.0
O18 A:DVT2001 4.5 20.0 1.0
NH2 A:ARG1141 4.5 0.3 1.0
O9 A:DVT2001 4.5 20.0 1.0
O17 A:DVT2001 4.5 20.0 1.0
CZ A:ARG1141 4.9 0.3 1.0

Vanadium binding site 4 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 4 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 4 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V7 A:DVT2001 0.0 20.0 1.0
O25 A:DVT2001 1.6 20.0 1.0
O11 A:DVT2001 1.8 20.0 1.0
O21 A:DVT2001 1.8 20.0 1.0
O24 A:DVT2001 2.0 20.0 1.0
O8 A:DVT2001 2.0 20.0 1.0
O7 A:DVT2001 2.2 20.0 1.0
V5 A:DVT2001 3.0 20.0 1.0
V6 A:DVT2001 3.1 20.0 1.0
V9 A:DVT2001 3.1 20.0 1.0
V2 A:DVT2001 3.1 20.0 1.0
V8 A:DVT2001 3.2 20.0 1.0
O6 A:DVT2001 3.3 20.0 1.0
O16 A:DVT2001 3.4 20.0 1.0
O20 A:DVT2001 3.5 20.0 1.0
O26 A:DVT2001 3.5 20.0 1.0
O2 A:DVT2001 3.7 20.0 1.0
O4 A:DVT2001 4.3 20.0 1.0
O14 A:DVT2001 4.3 20.0 1.0
O22 A:DVT2001 4.4 20.0 1.0
O13 A:DVT2001 4.4 20.0 1.0
O27 A:DVT2001 4.4 20.0 1.0
V4 A:DVT2001 4.4 20.0 1.0
O19 A:DVT2001 4.4 20.0 1.0
CZ A:ARG1141 4.5 0.3 1.0
O1 A:DVT2001 4.5 20.0 1.0
NH1 A:ARG1141 4.5 0.3 1.0
O23 A:DVT2001 4.5 20.0 1.0
O9 A:DVT2001 4.6 20.0 1.0
O17 A:DVT2001 4.6 20.0 1.0
NE A:ARG1141 4.6 0.3 1.0
NH2 A:ARG1141 4.9 0.3 1.0
CD A:ARG1141 4.9 0.3 1.0

Vanadium binding site 5 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 5 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 5 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V6 A:DVT2001 0.0 20.0 1.0
O22 A:DVT2001 1.6 20.0 1.0
O6 A:DVT2001 1.9 20.0 1.0
O21 A:DVT2001 1.9 20.0 1.0
O19 A:DVT2001 1.9 20.0 1.0
O20 A:DVT2001 2.0 20.0 1.0
O7 A:DVT2001 2.3 20.0 1.0
V8 A:DVT2001 3.1 20.0 1.0
V7 A:DVT2001 3.1 20.0 1.0
V4 A:DVT2001 3.1 20.0 1.0
V5 A:DVT2001 3.1 20.0 1.0
O24 A:DVT2001 3.6 20.0 1.0
O11 A:DVT2001 3.6 20.0 1.0
O17 A:DVT2001 3.6 20.0 1.0
O13 A:DVT2001 3.7 20.0 1.0
NH2 A:ARG1147 4.2 88.8 1.0
V2 A:DVT2001 4.4 20.0 1.0
O25 A:DVT2001 4.4 20.0 1.0
O12 A:DVT2001 4.4 20.0 1.0
O14 A:DVT2001 4.5 20.0 1.0
O23 A:DVT2001 4.5 20.0 1.0
NZ D:LYS1149 4.6 84.5 1.0
NE A:ARG1147 4.6 88.8 1.0
O16 A:DVT2001 4.6 20.0 1.0
O8 A:DVT2001 4.6 20.0 1.0
O9 A:DVT2001 4.6 20.0 1.0
O2 A:DVT2001 4.7 20.0 1.0
CZ A:ARG1147 4.8 88.8 1.0

Vanadium binding site 6 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 6 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 6 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V8 A:DVT2001 0.0 20.0 1.0
O23 A:DVT2001 1.7 20.0 1.0
O20 A:DVT2001 1.7 20.0 1.0
O17 A:DVT2001 1.9 20.0 1.0
O24 A:DVT2001 1.9 20.0 1.0
O2 A:DVT2001 2.1 20.0 1.0
O7 A:DVT2001 2.1 20.0 1.0
V10 A:DVT2001 3.0 20.0 1.0
O27 A:DVT2001 3.1 20.0 1.0
V6 A:DVT2001 3.1 20.0 1.0
V9 A:DVT2001 3.1 20.0 1.0
V4 A:DVT2001 3.1 20.0 1.0
O19 A:DVT2001 3.1 20.0 1.0
V2 A:DVT2001 3.1 20.0 1.0
O18 A:DVT2001 3.1 20.0 1.0
O21 A:DVT2001 3.2 20.0 1.0
V3 A:DVT2001 3.2 20.0 1.0
V7 A:DVT2001 3.2 20.0 1.0
O9 A:DVT2001 3.4 20.0 1.0
O8 A:DVT2001 3.4 20.0 1.0
O28 A:DVT2001 4.3 20.0 1.0
O22 A:DVT2001 4.3 20.0 1.0
O15 A:DVT2001 4.3 20.0 1.0
O6 A:DVT2001 4.3 20.0 1.0
V5 A:DVT2001 4.3 20.0 1.0
O13 A:DVT2001 4.4 20.0 1.0
O4 A:DVT2001 4.4 20.0 1.0
O16 A:DVT2001 4.4 20.0 1.0
O26 A:DVT2001 4.4 20.0 1.0
O3 A:DVT2001 4.4 20.0 1.0
V1 A:DVT2001 4.4 20.0 1.0
O1 A:DVT2001 4.4 20.0 1.0
O12 A:DVT2001 4.4 20.0 1.0
O11 A:DVT2001 4.4 20.0 1.0
O10 A:DVT2001 4.4 20.0 1.0
O25 A:DVT2001 4.5 20.0 1.0

Vanadium binding site 7 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 7 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 7 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V5 A:DVT2001 0.0 20.0 1.0
O14 A:DVT2001 1.6 20.0 1.0
O6 A:DVT2001 1.8 20.0 1.0
O11 A:DVT2001 1.9 20.0 1.0
O13 A:DVT2001 1.9 20.0 1.0
O16 A:DVT2001 2.1 20.0 1.0
O7 A:DVT2001 2.3 20.0 1.0
V7 A:DVT2001 3.0 20.0 1.0
V2 A:DVT2001 3.0 20.0 1.0
V4 A:DVT2001 3.1 20.0 1.0
V6 A:DVT2001 3.1 20.0 1.0
O21 A:DVT2001 3.6 20.0 1.0
O8 A:DVT2001 3.6 20.0 1.0
O19 A:DVT2001 3.6 20.0 1.0
O9 A:DVT2001 3.6 20.0 1.0
O25 A:DVT2001 4.3 20.0 1.0
V8 A:DVT2001 4.3 20.0 1.0
O12 A:DVT2001 4.4 20.0 1.0
O22 A:DVT2001 4.4 20.0 1.0
O24 A:DVT2001 4.5 20.0 1.0
O1 A:DVT2001 4.5 20.0 1.0
O20 A:DVT2001 4.5 20.0 1.0
O17 A:DVT2001 4.6 20.0 1.0
O2 A:DVT2001 4.7 20.0 1.0
NH1 A:ARG1138 4.9 0.0 1.0

Vanadium binding site 8 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 8 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 8 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V2 A:DVT2001 0.0 20.0 1.0
O16 A:DVT2001 1.7 20.0 1.0
O1 A:DVT2001 1.7 20.0 1.0
O8 A:DVT2001 1.9 20.0 1.0
O9 A:DVT2001 1.9 20.0 1.0
O7 A:DVT2001 2.1 20.0 1.0
O2 A:DVT2001 2.1 20.0 1.0
V5 A:DVT2001 3.0 20.0 1.0
O4 A:DVT2001 3.0 20.0 1.0
V1 A:DVT2001 3.0 20.0 1.0
O13 A:DVT2001 3.1 20.0 1.0
V9 A:DVT2001 3.1 20.0 1.0
V8 A:DVT2001 3.1 20.0 1.0
V4 A:DVT2001 3.1 20.0 1.0
V7 A:DVT2001 3.1 20.0 1.0
O3 A:DVT2001 3.1 20.0 1.0
V3 A:DVT2001 3.1 20.0 1.0
O11 A:DVT2001 3.2 20.0 1.0
O24 A:DVT2001 3.4 20.0 1.0
O17 A:DVT2001 3.4 20.0 1.0
O14 A:DVT2001 4.3 20.0 1.0
O5 A:DVT2001 4.3 20.0 1.0
O15 A:DVT2001 4.3 20.0 1.0
O27 A:DVT2001 4.3 20.0 1.0
O6 A:DVT2001 4.3 20.0 1.0
V10 A:DVT2001 4.4 20.0 1.0
O21 A:DVT2001 4.4 20.0 1.0
O26 A:DVT2001 4.4 20.0 1.0
O19 A:DVT2001 4.4 20.0 1.0
V6 A:DVT2001 4.4 20.0 1.0
O25 A:DVT2001 4.4 20.0 1.0
O23 A:DVT2001 4.4 20.0 1.0
O20 A:DVT2001 4.4 20.0 1.0
O18 A:DVT2001 4.4 20.0 1.0
O12 A:DVT2001 4.4 20.0 1.0
O10 A:DVT2001 4.5 20.0 1.0

Vanadium binding site 9 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 9 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 9 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V4 A:DVT2001 0.0 20.0 1.0
O12 A:DVT2001 1.6 20.0 1.0
O19 A:DVT2001 1.8 20.0 1.0
O13 A:DVT2001 1.8 20.0 1.0
O9 A:DVT2001 2.0 20.0 1.0
O17 A:DVT2001 2.0 20.0 1.0
O7 A:DVT2001 2.2 20.0 1.0
V5 A:DVT2001 3.1 20.0 1.0
V8 A:DVT2001 3.1 20.0 1.0
V2 A:DVT2001 3.1 20.0 1.0
V6 A:DVT2001 3.1 20.0 1.0
V3 A:DVT2001 3.1 20.0 1.0
O6 A:DVT2001 3.3 20.0 1.0
O20 A:DVT2001 3.4 20.0 1.0
O16 A:DVT2001 3.5 20.0 1.0
O10 A:DVT2001 3.6 20.0 1.0
O2 A:DVT2001 3.7 20.0 1.0
NZ D:LYS1149 3.9 84.5 1.0
O14 A:DVT2001 4.3 20.0 1.0
O18 A:DVT2001 4.3 20.0 1.0
O3 A:DVT2001 4.4 20.0 1.0
O22 A:DVT2001 4.4 20.0 1.0
V7 A:DVT2001 4.4 20.0 1.0
O21 A:DVT2001 4.4 20.0 1.0
O23 A:DVT2001 4.5 20.0 1.0
O11 A:DVT2001 4.5 20.0 1.0
O1 A:DVT2001 4.5 20.0 1.0
O24 A:DVT2001 4.5 20.0 1.0
O8 A:DVT2001 4.6 20.0 1.0

Vanadium binding site 10 out of 80 in 5wp6

Go back to Vanadium Binding Sites List in 5wp6
Vanadium binding site 10 out of 80 in the Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 10 of Cryo-Em Structure of A Human TRPM4 Channel in Complex with Calcium and Decavanadate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:V2001

b:20.0
occ:1.00
V3 A:DVT2001 0.0 20.0 1.0
O10 A:DVT2001 1.6 20.0 1.0
O3 A:DVT2001 1.8 20.0 1.0
O18 A:DVT2001 1.8 20.0 1.0
O9 A:DVT2001 2.0 20.0 1.0
O17 A:DVT2001 2.1 20.0 1.0
O2 A:DVT2001 2.2 20.0 1.0
V10 A:DVT2001 3.0 20.0 1.0
V1 A:DVT2001 3.1 20.0 1.0
V2 A:DVT2001 3.1 20.0 1.0
V4 A:DVT2001 3.1 20.0 1.0
V8 A:DVT2001 3.2 20.0 1.0
O15 A:DVT2001 3.3 20.0 1.0
O1 A:DVT2001 3.4 20.0 1.0
O23 A:DVT2001 3.5 20.0 1.0
O12 A:DVT2001 3.6 20.0 1.0
O7 A:DVT2001 3.7 20.0 1.0
O28 A:DVT2001 4.3 20.0 1.0
O13 A:DVT2001 4.3 20.0 1.0
O27 A:DVT2001 4.4 20.0 1.0
O4 A:DVT2001 4.4 20.0 1.0
O5 A:DVT2001 4.4 20.0 1.0
V9 A:DVT2001 4.4 20.0 1.0
O19 A:DVT2001 4.4 20.0 1.0
O16 A:DVT2001 4.5 20.0 1.0
O20 A:DVT2001 4.5 20.0 1.0
O8 A:DVT2001 4.6 20.0 1.0
O24 A:DVT2001 4.6 20.0 1.0

Reference:

P.A.Winkler, Y.Huang, W.Sun, J.Du, W.Lu. Electron Cryo-Microscopy Structure of A Human TRPM4 Channel. Nature V. 552 200 2017.
ISSN: ESSN 1476-4687
PubMed: 29211723
DOI: 10.1038/NATURE24674
Page generated: Thu Oct 29 07:05:59 2020

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