Vanadium in PDB 4rh7: Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI

The structure of Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI, PDB code: 4rh7 was solved by H.Schmidt, R.Zalyte, L.Urnavicius, A.P.Carter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.60 / 3.41
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	136.030, 487.150, 276.460, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 28.5

The structure of Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Vanadium atom in the Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI (pdb code 4rh7). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI, PDB code: 4rh7:

Vanadium binding site 1 out of 1 in the Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Crystal Structure of Human Cytoplasmic Dynein 2 Motor Domain in Complex with Adp.VI within 5.0Å range: probe atom residue distance (Å) B Occ A:V4401 b:55.7 occ:1.00 VG A:AOV4401 0.0 55.7 1.0 O3B A:AOV4401 2.0 62.0 1.0 O2G A:AOV4401 2.1 52.5 1.0 O3G A:AOV4401 2.1 57.0 1.0 O1G A:AOV4401 2.1 47.2 1.0 O4G A:AOV4401 2.1 41.9 1.0 PB A:AOV4401 2.9 64.4 1.0 NH1 A:ARG1867 3.0 77.5 1.0 NZ A:LYS1695 3.0 83.2 1.0 OE2 A:GLU1742 3.1 77.1 1.0 O1B A:AOV4401 3.2 69.6 1.0 O2B A:AOV4401 3.3 56.3 1.0 MG A:MG4402 3.4 31.1 1.0 NH2 A:ARG2109 3.5 85.1 1.0 OD1 A:ASN1792 3.9 97.0 1.0 CZ A:ARG1867 4.1 77.4 1.0 CD A:GLU1742 4.2 83.4 1.0 O3A A:AOV4401 4.3 63.3 1.0 OG1 A:THR1696 4.4 64.1 1.0 CE A:LYS1695 4.4 81.1 1.0 CZ A:ARG2109 4.4 81.9 1.0 NH2 A:ARG1867 4.5 86.9 1.0 ND2 A:ASN1792 4.6 0.9 1.0 OE1 A:GLU1742 4.6 90.1 1.0 N A:GLY1692 4.6 94.1 1.0 CG A:ASN1792 4.7 93.4 1.0 OD1 A:ASP1741 4.7 99.8 1.0 CB A:ALA2105 4.8 70.7 1.0 CA A:ALA1691 4.9 94.8 1.0 O2A A:AOV4401 4.9 65.8 1.0 NH1 A:ARG2109 4.9 79.3 1.0

H.Schmidt, R.Zalyte, L.Urnavicius, A.P.Carter. Structure of Human Cytoplasmic Dynein-2 Primed For Its Power Stroke Nature 2014.
ISSN: ESSN 1476-4687
DOI: 10.1038/NATURE14023