Vanadium in PDB 4c3w: Vanadium(IV)-Picolinate Complexed with Lysozyme

All present enzymatic activity of Vanadium(IV)-Picolinate Complexed with Lysozyme:
3.2.1.17;

The structure of Vanadium(IV)-Picolinate Complexed with Lysozyme, PDB code: 4c3w was solved by M.F.A.Santos, I.Correia, A.R.Oliveira, E.Garribba, J.C.Pessoa, M.J.Romao, T.Santos-Silva, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.94 / 1.28
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.120, 78.120, 37.320, 90.00, 90.00, 90.00
R / Rfree (%)	14.445 / 17.492

The structure of Vanadium(IV)-Picolinate Complexed with Lysozyme also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Sodium	(Na)	1 atom

The binding sites of Vanadium atom in the Vanadium(IV)-Picolinate Complexed with Lysozyme (pdb code 4c3w). This binding sites where shown within 5.0 Angstroms radius around Vanadium atom.
In total only one binding site of Vanadium was determined in the Vanadium(IV)-Picolinate Complexed with Lysozyme, PDB code: 4c3w:

Vanadium binding site 1 out of 1 in the Vanadium(IV)-Picolinate Complexed with Lysozyme


Mono view


Stereo pair view

A full contact list of Vanadium with other atoms in the V binding site number 1 of Vanadium(IV)-Picolinate Complexed with Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:V1130 b:5.4 occ:0.65 V A:AIV1130 0.0 5.4 0.7 O A:AIV1130 1.8 11.9 0.7 OD2 A:ASP52 1.9 9.6 1.0 O11 A:AIV1130 2.0 8.0 0.7 O2 A:AIV1130 2.0 6.4 0.7 N2 A:AIV1130 2.1 5.6 0.7 N12 A:AIV1130 2.2 7.8 0.7 C12 A:AIV1130 2.8 7.9 0.7 C2 A:AIV1130 2.8 5.4 0.7 C1 A:AIV1130 2.9 5.9 0.7 C11 A:AIV1130 2.9 8.4 0.7 CG A:ASP52 3.0 7.7 1.0 C13 A:AIV1130 3.1 6.8 0.7 C3 A:AIV1130 3.1 5.8 0.7 OD1 A:ASP52 3.5 11.1 1.0 O1 A:AIV1130 4.0 6.7 0.7 O12 A:AIV1130 4.0 12.3 0.7 ND2 A:ASN46 4.0 21.3 1.0 O A:HOH2169 4.2 30.1 1.0 CB A:ASP52 4.2 5.3 1.0 OE1 A:GLU35 4.3 7.1 1.0 C16 A:AIV1130 4.4 10.0 0.7 C6 A:AIV1130 4.4 7.0 0.7 C14 A:AIV1130 4.4 9.1 0.7 C4 A:AIV1130 4.4 7.0 0.7 O A:HOH2085 4.7 59.0 1.0 C15 A:AIV1130 4.9 10.8 0.7 O A:GLN57 4.9 5.1 1.0 C5 A:AIV1130 4.9 7.4 0.7 CB A:GLN57 4.9 3.8 1.0 CG A:ASN46 5.0 13.9 1.0

M.F.A.Santos, I.Correia, A.R.Oliveira, E.Garribba, J.C.Pessoa, T.Santos-Silva. Vanadium Complexes As Prospective Therapeutics: Structural Characterization of A V(IV) Lysozyme Adduct Eur.J.Inorg.Chem. V. 21 3293 2014.
ISSN: ISSN 1434-1948
DOI: 10.1002/EJIC.201402408