Vanadium in the structure of Crystal Structure of the Human Tyrosine Receptor Phosphate Gamma in Complex With Vanadate (pdb 2hy3)

The binding sites of Vanadium atom in the structure of Crystal Structure of the Human Tyrosine Receptor Phosphate Gamma in Complex With Vanadate (pdb code 2hy3). This binding sites where shown with 5.0 Angstroms radius around Vanadium atom. The 2hy3 structure was solved by X.JIN, T.MIN, A.BERA, H.MU, J.M.SAUDER, J.C.FREEMAN, C.REYES, D.SMITH, S.R.WASSERMAN, S.K.BURLEY, L.SHAPIRO, NEW YORK SGX RESEARCH CENTER FORSTRUCTURAL GENOMICS (NYSGXRC), with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 17.0-2.6 Space group P1211 a (A) 58.173 b (A) 74.787 c (A) 82.071 alpha (°) 90.00 beta (°) 99.58 gamma (°) 90.00 Rfactor (%) 20.2 Rfree (%) 28.8 Vanadium Binding Sites: Vanadium binding site 1 out of 2 in 2hy3 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Vanadium in the PDB 2hy3. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Vanadium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Cys1060, A: Ser1061, A: Ala1062, A: Gly1063, A: Val1064, A: Gly1065, A: Arg1066, A: Gln1104, A: Vo4158, conact list: Atom Atom Distance (A) V CB A:Cys1060 4.16 V SG A:Cys1060 2.98 V C A:Cys1060 4.96 V N A:Ser1061 3.97 V CB A:Ser1061 4.42 V C A:Ser1061 4.54 V CA A:Ser1061 4.53 V N A:Ala1062 3.68 V C A:Ala1062 4.60 V CB A:Ala1062 4.11 V CA A:Ala1062 4.28 V N A:Gly1063 4.20 V N A:Val1064 4.36 V CG2 A:Val1064 4.92 V C A:Val1064 4.79 V N A:Gly1065 3.67 V C A:Gly1065 4.73 V CA A:Gly1065 4.06 V N A:Arg1066 4.26 V CG A:Arg1066 4.91 V OE1 A:Gln1104 3.88 V CD A:Gln1104 4.97 V O1 A:Vo4158 1.95 V O2 A:Vo4158 1.91 V O4 A:Vo4158 1.90 V O3 A:Vo4158 1.94 V V A:Vo4158 0.00 interactive model: Vanadium binding site 2 out of 2 in 2hy3 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Vanadium in the PDB 2hy3. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Vanadium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Cys1060, B: Ser1061, B: Ala1062, B: Gly1063, B: Val1064, B: Gly1065, B: Arg1066, B: Vo4159, conact list: Atom Atom Distance (A) V CB B:Cys1060 4.14 V SG B:Cys1060 2.93 V N B:Ser1061 4.22 V CB B:Ser1061 4.78 V C B:Ser1061 4.70 V CA B:Ser1061 4.77 V N B:Ala1062 3.82 V C B:Ala1062 4.48 V CB B:Ala1062 3.93 V CA B:Ala1062 4.24 V N B:Gly1063 3.86 V C B:Gly1063 4.98 V CA B:Gly1063 4.77 V N B:Val1064 4.12 V CG2 B:Val1064 4.47 V C B:Val1064 4.60 V CA B:Val1064 4.83 V N B:Gly1065 3.63 V C B:Gly1065 4.58 V CA B:Gly1065 4.10 V N B:Arg1066 4.02 V O1 B:Vo4159 1.91 V O2 B:Vo4159 1.93 V O4 B:Vo4159 1.93 V O3 B:Vo4159 1.93 V V B:Vo4159 0.00 interactive model: